1712 - 1748 (36 years)
| Martha Patsy Jefferson 1772-1836 |
| Martha Patsy Jefferson | |
| B: | 27 Sep 1772 |
| Charlottesville, Independent Cities, Virginia, USA | |
| D: | 10 Oct 1836 |
| Charlottesville, Independent Cities, Virginia, USA | |
 | Thomas Mann Randolph 1768-1828 |
| Thomas Mann Randolph | |
| B: | 17 May 1768 |
| Tuckahoe, Goochland, Virginia, USA | |
| M: | 23 Feb 1790 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| D: | 20 Jun 1828 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| Jane Randolph Jefferson 1774-1775 |
| Jane Randolph Jefferson | |
| B: | 3 Apr 1774 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| D: | Sep 1775 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| _____ Jefferson 1777-1777 |
| _____ Jefferson | |
| B: | 28 May 1777 |
| Charlottesville, Independent Cities, Virginia, USA | |
| D: | 14 Jun 1777 |
| Charlottesville, Independent Cities, Virginia, USA | |
| Mary Jefferson 1778-1871 |
| Mary Jefferson | |
| B: | 1 Aug 1778 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| D: | 15 Apr 1871 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| John Wayles Eppes 1773-1823 |
| John Wayles Eppes | |
| B: | 7 Apr 1773 |
| City Point, Virginia, USA | |
| M: | 13 Oct 1797 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| D: | 5 Sep 1823 |
| Millbrook, Buckingham, Virginia, USA | |
| Lucy Elizabeth Jefferson, I 1780-1804 |
| Lucy Elizabeth Jefferson, I | |
| B: | 3 Nov 1780 |
| Richmond, Henrico, Virginia, USA | |
| D: | 17 Apr 1804 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| Lucy Elizabeth Jefferson, II 1782-Abt 1784 |
| Lucy Elizabeth Jefferson, II | |
| B: | 8 May 1782 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| D: | Abt 13 Oct 1784 |
| Eppington, Winterpock, Chesterfield, Virginia, USA | |
| Martha Skelton Wayles 1748-1782 |
| Martha Skelton Wayles | |
| B: | 30 Oct 1748 |
| Charles City, Virginia, USA | |
| D: | 6 Sep 1782 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| Thomas Jefferson 1743-1826 |
| Thomas Jefferson | |
| B: | 13 Apr 1743 |
| Shadwell, Albemarle, Virginia, USA | |
| M: | Jan 1772 |
| The Forest, Charles City, Virginia, USA | |
| D: | 4 Jul 1826 |
| Monticello, Charlottesville, Albemarle, Virginia, USA | |
| Martha Eppes 1712-1748 |
| Martha Eppes | |
| B: | 1712 |
| D: | 1748 |
| John Wayles 1715-1773 |
| John Wayles | |
| B: | 1715 |
| D: | 1773 |
